Matthew F. Daley, MD

Senior Clinician Investigator

BaylissMatthew F. Daley, MD, is a Senior Clinician Investigator at the Institute for Health Research. He conducts research on a broad range of pediatric-oriented topics. He has focused particularly on vaccine-related topics, including vaccine safety, vaccine delivery, and parental vaccine hesitancy. For many years, he has also worked to expand the use of multi-institutional electronic health record data for public health surveillance and research purposes.

Dr. Daley received his medical training at Stanford University School of Medicine and completed a residency and chief residency in Pediatrics at the University of Colorado.

Dr. Daley is a practicing pediatrician at Kaiser Permanente Colorado, and an Associate Professor in the Department of Pediatrics at the University of Colorado School of Medicine. He is a Fellow in the American Academy of Pediatrics and a member of the Pediatrics Association. He is also the chairperson of the Immunization Technical Advisory Group for the state of Colorado, and has served as a subject matter expert for the World Health Organization regarding global influenza vaccine hesitancy, acceptance, and demand.


Selected Research

  • Vaccine Safety Datalink Project

    The major goal of this project is to evaluate the safety of currently licensed vaccines in the U.S. To accomplish this, we lead specific vaccine safety studies, and use privacy-protecting approaches to contribute electronic clinical data to multiple vaccine safety investigations.
    Funder: Centers for Disease Control and Prevention
    Study End Date: 09/27/2022

  • Vaccine Safety Datalink Infrastructure for Studying the Safety of the Immunization Schedule

    The objective of this project is to develop the infrastructure to supplement existing epidemiologic data with patient-reported information on under-vaccination and the use of alternative vaccination schedules.
    Funder: Centers for Disease Control and Prevention
    Study End Date: 09/24/2019

  • Vaccine Safety Datalink Assessment of Influenza Vaccination Status

    The goal of this project is to assess through survey the accuracy of existing influenza vaccination data among adults and pregnant women, to improve the ability of the Centers for Disease Control and Prevention to monitor national influenza vaccination rates.
    Funder: Centers for Disease Control and Prevention
    Study End Date: 09/19/2020

  • Patient Outcomes Research to Advance Learning (PORTAL) Network

    The PORTAL research network brings together leading health-care delivery systems to study the effectiveness of different approaches to diagnosis, treatment and management, in order to assist patients, their caregivers, and doctors in making better-informed decisions. The PORTAL network consists of Kaiser Permanente, HealthPartners, and Denver Health; these health care systems collectively care for >12 million members.
    Funder: Patient-Centered Outcomes Research Institute (PCORI)
    Study End Date: 04/07/2019

  • Childhood Obesity Data Initiative (CODI)

    The objective of the CODI project is to develop and implement a reusable system of data integration across multiple sectors focused on childhood obesity and prevention. The CODI project will include health care organizations and entities providing healthy weight related interventions, with the goal of providing an integrated, de-duplicated, longitudinal record of care for individuals across organizations, to be used for research and public health surveillance purposes.
    Funder: Public Health Informatics Institute
    Study End Date: 09/30/2020