Elizabeth BaylissElizabeth A. Bayliss, MD, MSPH

Elizabeth A. Bayliss, MD, MSPH, is the Director for Scientific Development and an Investigator in the Institute for Health Research. She is trained in Family Medicine and is an Associate Professor of Family Medicine at the University of Colorado at Denver Health Sciences Center. Her research interests include investigating processes of care for persons with multiple chronic medical conditions as well as methods of measuring morbidity.

Institute for Health Research
10065 E. Harvard Ave Suite 300
Denver, CO 80231
elizabeth.bayliss @ kp.org



Health outcomes for complex patients: Continuity of care and patient perspectives.
Assess health outcomes in complex patients as a function of multiple different subjective factors such mediated by different types of continuity of care.
Funder: Agency for Healthcare Research and Quality

Scalable PArtnering Network for CER: Across Lifespan, Conditions, and Settings.
This project will develop a distributed research network, which will create linkages across health care systems to provide access to current patient-level data that supports a dynamic foundation for conducting observational investigations and improves recruitment for interventional research. Over time, the network will expand to facilitate study of broad spectrums of treatments for multiple health conditions in complex and diverse populations across multiple types of health delivery systems.
Funder: Agency for Healthcare Research and Quality

Determining Processes of Cardiovascular Care Relevant to Complex Patients.

We will study an historical cohort of adults with an initial diagnosis of cancer during the period 1999 to 2007. We will a) assess the attainment of goals for specific components of primary, secondary, and ‘tertiary’ prevention of coronary heart disease as a function of cancer prognosis, overall morbidity and the interaction between them, and b) assess the comparative effectiveness of these coronary heart disease prevention interventions on a composite coronary heart disease outcome.
Funder: Agency for Healthcare Research and Quality

Investigation of patient-reported pain outcomes to inform diabetic peripheral neuropathy treatment and research.
This project is exploring strategies for validating and collecting patient-reported pain outcomes to facilitate comparative effectiveness and safety studies related to painful DPN in diverse patient populations.
Funder: Kaiser Permanente National

HMO Research Network CERT III Anti –TNF.
There are two broad aims for CERT3: 1) Enhance the collective ability of the HMO Research Network and other collaborating health plans to advance therapeutics knowledge by leveraging unique data sources within a very large, generalizable population. 2) Develop and implement new multi-faceted methods for disseminating and promoting best therapeutic practices.
Funder: Agency for Healthcare Research and Quality

Evaluation of care needs of KPCO members with regard to the Affordable Care Act.

Funder: Kaiser Permanente Colorado


The effect of incident comorbidities on guideline-concordant chronic disease care.
Assess the effect of incident depression, treatable cancer, and pulmonary disease exacerbations on guideline-concordant care for persons with diabetes.
Funder: Agency for Healthcare Research and Quality

The influence of glycemic control on surgical complications, revisions, and hosptial re-admissions following total joint replacement in diabetic patients.

This project is assessing post-operative complications for total knee or total hip arthroplasty as a function of diabetes control.
Funder: Kaiser Permanente National

Assessing barriers to self-management of comorbidities.

Assess barriers to the medical self-management process for several different populations of persons with multiple medical conditions.
Funder: Agency for Healthcare Research and Quality

Patient-centered care management for seniors with multimorbidities.

Assesses the medical care needs and processes for a geriatric population with multiple medical conditions.
Funder: National Institute of Health/ National Institute on Aging

American Academy of Family Physicians/Research Stimulation Grant

Assessment of self-management issues in patients with comorbid chronic diseases.
Qualitative investigation into barriers to self-management for persons with multiple medical conditions.
Sullivan PW, Ghushchyan VH, Bayliss EA. The Impact of Comorbidity Burden on Preference-Based HRQL in the United States. PharmacoEconomics. 2012; 30(5): 431-442.  PMID: 22452633

Toh S, Li L, Harrold L, Bayliss EA, Curtis JR, Liu L, Platt R, Herrinton L. Comparative safety of Infliximab and Etanercept on the risk of serious infections – Does the association vary by patient characteristics? Pharmacoepidemiol and Drug Safety. 2012; 21(5): 524-534 PMID: 22411435

Bayliss EA, Ellis JL, Shoup JA, Zeng C, McQuillan DB, Steiner JF.  Association of Patient-centered Outcomes with Patient-reported and ICD-9 Based Morbidity Measures.  Annals of Family Medicine. 2012; 10(2): 126-133 PMID: 22412004  

Loeb DF, Bayliss EA, Binswanger IA, Candrian C, Degruy FV. Primary Care Physician Perceptions on Caring for Complex Patients with Medical and Mental Illness.  J Gen Intern Med. 2012 Feb 28. [Epub ahead of print] PMID: 22370766

Bayliss EA.  Simplifying Care for Complex Patients (editorial).  Annals of Family Medicine. 2012; 10(1):3-5 PMID: 22230824  

Raebel MA, Ellis JL, Carroll NM et al. Characteristics of Patients with Primary Non-adherence to Medications for Hypertension, Diabetes, and Lipid Disorders. J Gen Intern Med. 2012; 27(1):57-64. PMID:21879374 

Raebel MA, Carroll NM, Ellis JL, Schroeder EB, Bayliss EA. Importance of including early nonadherence in estimations of medication adherence. Ann Pharmacother. 2011; 45(9):1053-1060. PMID:21852598

Newcomer SR, Steiner JF, Bayliss EA. Identifying subgroups of complex patients with cluster analysis. Am J Manag Care, 2011; 17(8):e324-e332. PMID:21851140

Bayliss EA, Bhardwaja B, Ross C, Beck A, Lanese DM. Multidisciplinary team care may slow the rate of decline in renal function. Clin J Am Soc Nephrol. 2011; 6(4):704-710.  PMID:21273376

Bayliss EA, Blatchford PJ, Newcomer SR, Steiner JF, Fairclough DL. The effect of incident cancer, depression and pulmonary disease exacerbations on type 2 diabetes control. J Gen Intern Med. 2011; 26(6):575-581. PMID:21203859 

Soubhi H, Bayliss EA, Fortin M et al. Learning and caring in communities of practice: using relationships and collective learning to improve primary care for patients with multimorbidity. Ann Fam Med, 2010; 8(2):170-177. PMID:20212304  

Bayliss EA, Ellis JL, Delate T, Steiner JF, Raebel MA. Characteristics of Medicare Part D beneficiaries who reach the drug benefit threshold in both of the first two years of the Part D benefit. Med Care. 2010; 48(3):267-272. PMID:20125044

Raebel MA, Delate T, Ellis JL, Bayliss EA. Effects of reaching the drug benefit threshold on Medicare members' healthcare utilization during the first year of Medicare Part D. Med Care. 2008; 46(10):1116-1122. PMID:18815534

Bayliss EA, Ellis JL, Steiner JF. Seniors' self-reported multimorbidity captured biopsychosocial factors not incorporated into two other data-based morbidity measures. J Clin Epidemiol. 2009; 62(5):550-557.  PMID:18757178   

Bayliss EA, Edwards AE, Steiner JF, Main DS. Processes of care desired by elderly patients with multimorbidities. Fam Pract. 2008; 25(4):287-293. PMID:18628243   

Bayliss EA, Bosworth HB, Noel PH, Wolff JL, Damush TM, Mciver L. Supporting self-management for patients with complex medical needs: recommendations of a working group. Chronic Illn. 2007; 3(2):167-175. PMID:18083671

Bayliss EA, Ellis JL, Steiner JF. Barriers to self-management and quality-of-life outcomes in seniors with multimorbidities. Ann Fam Med. 2007; 5(5):395-402. PMID:17893380

Fortin M, Hudon C, Bayliss EA, Soubhi H, Lapointe L. Caring for body and soul: the importance of recognizing and managing psychological distress in persons with multimorbidity. Int J Psychiatry Med. 2007; 37(1):1-9. PMID:17645193

Fortin M, Soubhi H, Hudon C, Bayliss EA, van den Akker M. Multimorbidity's many challenges. BMJ 2007; 334(7602):1016-1017. PMID:17510108

Bayliss EA, Ellis JL, Steiner JF, Main DS. Initial validation of an instrument to identify barriers to self-management for persons with co-morbidities. Chronic Illn 2005; 1(4):315-320. PMID:17152455

Bayliss EA, Ellis JL, Steiner JF. Subjective assessments of comorbidity correlate with quality of life health outcomes: initial validation of a comorbidity assessment instrument. Health Qual Life Outcomes 2005; 3:51. PMID:16137329

Estabrooks PA, Nelson CC, Xu S et al. The frequency and behavioral outcomes of goal choices in the self-management of diabetes. Diabetes Educ 2005; 31(3):391-400. PMID:15919639

Bayliss EA, Bayliss MS, Ware JE, Jr., Steiner JF. Predicting declines in physical function in persons with multiple chronic medical conditions: what we can learn from the medical problem list. Health Qual Life Outcomes 2004; 2:47. PMID:15353000

Bayliss EA, Steiner JF, Fernald DH, Crane LA, Main DS. Descriptions of barriers to self-care by persons with comorbid chronic diseases. Ann Fam Med 2003;1(1):15-21. PMID:15043175

Bayliss EA. Proposals for US National Health Insurance. JAMA 2003;290(21):2799-2800. PMID:14657059

Bayliss EA, Park MK, Westfall JM, Zamorkski MA. Clinical inquiries. How can I improve patient adherence to prescribed medication? J Fam Pract 2001;50(4):303-304. PMID:11300979

Bayliss EA, Hambidge KM, Sokol RJ, Stewart B, Lilly JR. Hepatic concentrations of zinc, copper and manganese in infants with extrahepatic biliary atresia. J Trace Elem Med Biol 1995;9(1):40-43. PMID:8846156