Featured Publications


An update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer.


Burnett-Hartman AN, Lee JK, Demb J, Gupta S. An update on the epidemiology, molecular characterization, diagnosis, and screening strategies for early-onset colorectal cancer. Gastroenterology. 2021 Jan 5:S0016-5085(21)00008-1. doi: 10.1053/j.gastro.2020.12.068. Epub ahead of print. PMID: 33417940.

Conclusion:

Rising trends in the incidence and mortality of early-onset colorectal cancer (CRC) in those who are ages less than 50 years have been well-established. These trends have spurred intense investigation focused on elucidating the epidemiology and characteristics of early-onset CRC, as well on identifying strategies for early detection and prevention. In this review, we provide a contemporary update on early-onset CRC with a particular focus on epidemiology, molecular characterization, red flag signs and symptoms, and screening for early-onset CRC.

Restrictive Opioid Prescribing Policies and Evolving Risk Environments: A Qualitative Study of the Perspectives of Patients who Experienced an Accidental Opioid Overdose.


Mueller SR, Glanz JM, Nguyen AP, Stowell M, Koester S, Rinehart DJ, Binswanger IA. Restrictive opioid prescribing policies and evolving risk environments: A qualitative study of the perspectives of patients who experienced an accidental opioid overdose. Int J Drug Policy. 2021 Jan 7:103077. doi: 10.1016/j.drugpo.2020.103077. Epub ahead of print. PMID: 33423916.

Conclusion:

For some patients, macro-level policies and guidelines designed to reduce opioid overdoses by restricting opioid supply may have paradoxically created a micro-level risk environment that contributed to overdose events in a subset of patients.